BDBM20977 8-[butyl(ethyl)amino]-4-(2,6-dimethoxypyridin-3-yl)-6-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-2-one::CHEMBL186097::Pyridopyrazinone, 2a

SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(OC)nc1OC

InChI Key InChIKey=HVEZDGRGPISTDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20977   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20977(CHEMBL186097 | 8-[butyl(ethyl)amino]-4-(2,6-dimeth...)
Affinity DataIC50: 0.820nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20977(CHEMBL186097 | 8-[butyl(ethyl)amino]-4-(2,6-dimeth...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed