BDBM209510 US10328074, Example III-51::US11077107, Example III-51::US9266891, III-51

SMILES Cc1nnc2c(N[C@@H]3CCOC3)nc(cn12)-c1nc2cnc(cc2n1Cc1cccnc1)N1CCOCC1

InChI Key InChIKey=VSKQFDSORJPDSV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 209510   

TargetBromodomain-containing protein 4 [44-168]/Histone H4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM209510(US9266891, III-51 | US10328074, Example III-51 | U...)
Affinity DataIC50: 13nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM209510(US9266891, III-51 | US10328074, Example III-51 | U...)
Affinity DataIC50: 13nMAssay Description:This assay is used to determine whether the compounds inhibit the interaction between the first (BRD4-BD1) or the second (BRD4-BD2) bromodomain of BR...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM209510(US9266891, III-51 | US10328074, Example III-51 | U...)
Affinity DataIC50: 13nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In DepthDetails
US Patent