BDBM209002 US9233167, a-6-mPEG3-O-Codeine

SMILES COCCOCCOCCOCCOCCO[C@H]1C=CC2C3Cc4ccc(OC)c5OC1[C@]2(CCN3C)c45

InChI Key InChIKey=BEBMAWFZUQPURR-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 209002   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM209002(US9233167, a-6-mPEG3-O-Codeine)
Affinity DataEC50:  2.32E+4nMT: 2°CAssay Description:Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM209002(US9233167, a-6-mPEG3-O-Codeine)
Affinity DataKi:  2.43E+3nM ΔG°:  -7.65kcal/moleT: 2°CAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetKappa-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM209002(US9233167, a-6-mPEG3-O-Codeine)
Affinity DataKi:  5.91E+4nM ΔG°:  -5.76kcal/moleT: 2°CAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
In DepthDetails
US Patent