BDBM208991 US9233167, a-6-mPEG2-O-Hydroxycodone

SMILES COCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(OC)c5O[C@@H]1[C@]2(CCN3C)c45

InChI Key InChIKey=MPILMDKSPMDUJF-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208991   

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM208991(US9233167, a-6-mPEG2-O-Hydroxycodone)
Affinity DataEC50:  5.01E+3nMT: 2°CAssay Description:Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMu-type opioid receptor(Human)
Nektar Therapeutics

US Patent
LigandPNGBDBM208991(US9233167, a-6-mPEG2-O-Hydroxycodone)
Affinity DataKi:  632nM ΔG°:  -8.45kcal/moleT: 2°CAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
In DepthDetails
US Patent