BDBM207839 US9266828, B

SMILES [#6]-[#6](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#7]-[#6](-[#7])=[#7])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(cc1)\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-c1ccc(-[#6](-[#7])=[#7])c(F)c1

InChI Key InChIKey=JBZBMYMLCWBKFW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207839   

TargetFurin(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM207839(US9266828, B)
Affinity DataIC50: 3.70nMpH: 7.5 T: 2°CAssay Description:Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details
Go to US Patent

TargetFurin(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM207839(US9266828, B)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human furin using Pyr-RTKR-AMC as substrate preincubated for 30 mins followed by substrate addition and measured by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed