BDBM20730 (1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1,3-benzothiazol-2-yl]amino}phenyl)phenyl]carbonyl}cyclopentane-1-carboxylic acid::Biaryl keto acid derivative, 1

SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(Nc2nc3ccc(OC(F)(F)F)cc3s2)c(F)c1

InChI Key InChIKey=DMGWDGVBODDSLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20730   

TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20730((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...)
Affinity DataIC50: 73nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20730((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...)
Affinity DataIC50: 207nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed