BDBM20698 Tertiary Amide Analog, 41::sodium (3R,5R)-7-{3-[benzyl(propan-2-yl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}-3,5-dihydroxyheptanoate

SMILES CC(C)N(Cc1ccccc1)C(=O)c1nn(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C(C)C)-c1ccc(F)cc1

InChI Key InChIKey=RUTQTRSUIHEZES-UHFFFAOYSA-M

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20698   

LigandPNGBDBM20698(sodium (3R,5R)-7-{3-[benzyl(propan-2-yl)carbamoyl]...)
Affinity DataIC50: 9.80nM EC50:  10nMpH: 7.2 T: 2°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed