BDBM20585 2-phenyl-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol::CHEMBL316080::tetrahydroisoquinoline derivative, 17a
SMILES Oc1ccc2C(N(CCc2c1)c1ccccc1)c1ccc(OCCN2CCCC2)cc1
InChI Key InChIKey=HMBSMLATJKWAHH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 20585
Affinity DataIC50: 21nM EC50: 10.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 166nM EC50: 291nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 291nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 10.7nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of binding to human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataIC50: 21.0nMAssay Description:Inhibition of binding to human estrogen receptor alphaMore data for this Ligand-Target Pair