BDBM2055 13-[(benzenesulfinyl)methyl]-5-chloro-2-ethyl-9-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-10-one::2,8-disubstituted dipyridodiazepinone 38::2-Chloro-5,11-dihydro-11-ethyl-5-methyl-8-(phenylsulfinyl)-methyl-6H-dipyrido[3,2-b:2 ,3 -e][1,4]diazepin-6-one::CHEMBL103808

SMILES CCN1c2nc(Cl)ccc2N(C)C(=O)c2cc(CS(=O)c3ccccc3)cnc12

InChI Key InChIKey=PJHNLYXCFFTMJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 2055   

TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2055(CHEMBL103808 | 2-Chloro-5,11-dihydro-11-ethyl-5-me...)
Affinity DataIC50: 70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2055(CHEMBL103808 | 2-Chloro-5,11-dihydro-11-ethyl-5-me...)
Affinity DataIC50: 140nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [600-1027,Y787L]/[600-1155,Y787L](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2055(CHEMBL103808 | 2-Chloro-5,11-dihydro-11-ethyl-5-me...)
Affinity DataIC50: 2.42E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM2055(CHEMBL103808 | 2-Chloro-5,11-dihydro-11-ethyl-5-me...)
Affinity DataIC50: 140nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed