BDBM205474 PPiase inhibitor, 18

SMILES CCCCN(CCCC)c1nc(nc(n1)-c1cccn1-c1cc(C)cc(C)c1)N1CCCCCC1

InChI Key InChIKey=ZFMHXRROXGHVOR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 205474   

TargetInorganic pyrophosphatase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Kentucky

LigandPNGBDBM205474(PPiase inhibitor, 18)
Affinity DataIC50: 5.80E+4nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetInorganic pyrophosphatase(Escherichia coli (strain K12))
University of Kentucky

LigandPNGBDBM205474(PPiase inhibitor, 18)
Affinity DataIC50: 6.80E+4nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetInorganic pyrophosphatase(Baker's yeast)
University of Kentucky

LigandPNGBDBM205474(PPiase inhibitor, 18)
Affinity DataIC50: 3.28E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetProbable manganese-dependent inorganic pyrophosphatase(Staphylococcus aureus (strain MRSA252))
University of Kentucky

LigandPNGBDBM205474(PPiase inhibitor, 18)
Affinity DataIC50: 6.00E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed