BDBM205464 PPiase inhibitor, 1

SMILES C1CN1c1nc(nc(n1)-c1cccn1-c1ccccc1)N1CC1

InChI Key InChIKey=DAZONCQAIYYVKR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 205464   

TargetInorganic pyrophosphatase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50: 1.30E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetInorganic pyrophosphatase(Escherichia coli (strain K12))
University of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50: 2.33E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetInorganic pyrophosphatase(Baker's yeast)
University of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50: 3.55E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetProbable manganese-dependent inorganic pyrophosphatase(Staphylococcus aureus (strain MRSA252))
University of Kentucky

LigandPNGBDBM205464(PPiase inhibitor, 1)
Affinity DataIC50: 6.00E+5nMpH: 7.5 T: 2°CAssay Description:The compounds were first mixed with tetrasodium PPi (final concentration of 100 μM) at concentrations specified in the text in the reaction buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed