BDBM205372 US9249151, 18

SMILES CNC(C)C(=O)Nc1cc(cc(NC(=O)c2ccc(Cl)cn2)n1)-c1cnc2cccc(Cl)n12

InChI Key InChIKey=CYWOHIFFMYGOOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205372   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205372(US9249151, 18)
Affinity DataIC50: 78nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM205372(US9249151, 18)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In DepthDetails
US Patent