BDBM204708 (S) 1-[4-chloro-3-(4-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-1-yl)-phenoxy]-propan-2-ol::US9540379, 103

SMILES C[C@H](O)COc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccc(Cl)cc3n12

InChI Key InChIKey=GDSDBZHPAZMARE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204708   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM204708(US9540379, 103 | (S) 1-[4-chloro-3-(4-methyl-[1,2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DNA of PDE10A1 (AB 020593, 2340 bp) was synthesized and cloned into the vector pCR4. TOPO (Entelechon GmbH, Regensburg, Germany). The gene was th...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM204708(US9540379, 103 | (S) 1-[4-chloro-3-(4-methyl-[1,2,...)
Affinity DataIC50: 17nMAssay Description:The DNA encoding PDE2A (NM002599) was cloned and the gene was inserted in the baculovirus and the enzyme-protein expressed in SF21-cells. The enzyme ...More data for this Ligand-Target Pair
In DepthDetails
US Patent