BDBM20387 3-isoquinolin-5-yl-1-{phenyl[4-(trifluoromethyl)phenyl]methyl}urea::isoquinoline antagonist, 5e

SMILES FC(F)(F)c1ccc(cc1)C(NC(=O)Nc1cccc2cnccc12)c1ccccc1

InChI Key InChIKey=GDMIQADOPFXIJS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20387   

LigandPNGBDBM20387(3-isoquinolin-5-yl-1-{phenyl[4-(trifluoromethyl)ph...)
Affinity DataEC50:  147nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2008
Entry Details Article
PubMed