BDBM202587 US10035761, Compound 12c::US9238625, 12c

SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCSCC

InChI Key InChIKey=AVTXNQCMEJNGRM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 202587   

TargetSodium-dependent serotonin transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202587(US9238625, 12c | US10035761, Compound 12c)
Affinity DataKi:  3.31nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent serotonin transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202587(US9238625, 12c | US10035761, Compound 12c)
Affinity DataKi:  3.31nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202587(US9238625, 12c | US10035761, Compound 12c)
Affinity DataKi:  116nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202587(US9238625, 12c | US10035761, Compound 12c)
Affinity DataKi:  116nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202587(US9238625, 12c | US10035761, Compound 12c)
Affinity DataKi:  1.42E+3nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202587(US9238625, 12c | US10035761, Compound 12c)
Affinity DataKi:  1.42E+3nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In DepthDetails
US Patent