BDBM202586 US10035761, Compound 12b::US9238625, 12b

SMILES CCSCCCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)cc1

InChI Key InChIKey=RRPTVDCSIRLPCO-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 202586   

TargetSodium-dependent serotonin transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202586(US9238625, 12b | US10035761, Compound 12b)
Affinity DataKi:  18.8nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent serotonin transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202586(US9238625, 12b | US10035761, Compound 12b)
Affinity DataKi:  18.8nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202586(US9238625, 12b | US10035761, Compound 12b)
Affinity DataKi:  51.9nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202586(US9238625, 12b | US10035761, Compound 12b)
Affinity DataKi:  51.9nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202586(US9238625, 12b | US10035761, Compound 12b)
Affinity DataKi:  67.6nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM202586(US9238625, 12b | US10035761, Compound 12b)
Affinity DataKi:  67.6nMAssay Description:The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...More data for this Ligand-Target Pair
In DepthDetails
US Patent