BDBM202553 (E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide (4)
SMILES CN(C)C(=O)C(=C\c1ccc(o1)-c1nc2cnc3[nH]ccc3c2n1C1CCCCC1)\C#N
InChI Key InChIKey=GJMZWYLOARVASY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 202553
Affinity DataIC50: 9nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Affinity DataIC50: 346nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Affinity DataIC50: 0.127nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Affinity DataIC50: 459nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Affinity DataKd: 69.7nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
Affinity DataKd: 242nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
Affinity DataKd: 1.34nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
Affinity DataKd: 360nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
Affinity DataIC50: 764nMAssay Description:Inhibition of JAK3 in mouse BaF3 cells assessed as reduction in cell viability by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of JAK3 in mouse BaF3 cells assessed as reduction in cell viability in presence of 0.1 mM H2O2 by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 343nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 807nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IL6-stimulated STAT3 signalling in human CD4+ T cellsMore data for this Ligand-Target Pair