BDBM20193 1, Ac-pTyr-Leu-Pro-Gln-Thr-Val-NH2::4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[(1S,2S)-1-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]carbamoyl}pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid::BMCL13633 gp130 (904) derived peptide, 6::CHEMBL502473
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](C(C)C)C(N)=O
InChI Key InChIKey=QTNRFRVPGRRMLR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 20193
Affinity DataIC50: 290nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.8 T: 2°CAssay Description:His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Human)
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Stat3 by fluorescence polarization assayMore data for this Ligand-Target Pair