BDBM201550 US9540373, 27::US9879026, Example 27::USRE47636, Example 27

SMILES Fc1cc(ccc1C[C@H](NC(=O)C12CCC(CC1)CN2)C#N)-c1ccc2COC3(CCN(CC3)C3COC3)c2c1

InChI Key InChIKey=VCBLPORJGXYQEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 201550   

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201550(US9540373, 27 | US9879026, Example 27 | USRE47636,...)
Affinity DataIC50: 2.90nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201550(US9540373, 27 | US9879026, Example 27 | USRE47636,...)
Affinity DataIC50: 2.90nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201550(US9540373, 27 | US9879026, Example 27 | USRE47636,...)
Affinity DataIC50: 2.90nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In DepthDetails
US Patent