BDBM201019 US9540373, 8::US9879026, Example 8::USRE47636, Example 8

SMILES CN1CCC2(CC1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1

InChI Key InChIKey=HDXINRXLBDJTBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 201019   

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201019(US9540373, 8 | US9879026, Example 8 | USRE47636, E...)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201019(US9540373, 8 | US9879026, Example 8 | USRE47636, E...)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201019(US9540373, 8 | US9879026, Example 8 | USRE47636, E...)
Affinity DataIC50: 0.700nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
In DepthDetails
US Patent