BDBM200906 US9233946, 5

SMILES CC(C)c1ccc2sc(c(C)c2c1)S(=O)(=O)Nc1cccc(c1)C(O)=O

InChI Key InChIKey=GMPUAEBALQTUPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 200906   

LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50: 30nMAssay Description:The kinase activity of the bi-functional enzyme is readily quantified based on the production of F-2,6-P2 as described by Van Schaftingen et al. (198...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50: 60nMAssay Description:The kinase activity of the bi-functional enzyme is readily quantified based on the production of ADP and F-2,6-P2 from ATP and F6P. The ADP is detect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50: 30nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PFKFB3 in human PANC-1 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed