BDBM200598 US10011604, 25::US10590139, Example 25::US9227975, 25::US9796723, 25

SMILES OC1CCN(CC1)C(=O)Nc1cnc2ccc(nn12)N1CCC[C@@H]1c1cc(F)ccc1F

InChI Key InChIKey=ZSQPJEXCTAOQSR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 200598   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM200598(US9227975, 25 | US9796723, 25 | US10011604, 25 | U...)
Affinity DataIC50: 13.8nMpH: 7.5Assay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM200598(US9227975, 25 | US9796723, 25 | US10011604, 25 | U...)
Affinity DataIC50: 13.8nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (either TrkA or TrkB from Invitrogen Corp.) and...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM200598(US9227975, 25 | US9796723, 25 | US10011604, 25 | U...)
Affinity DataIC50: 13.8nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM200598(US9227975, 25 | US9796723, 25 | US10011604, 25 | U...)
Affinity DataIC50: 13.8nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM200598(US9227975, 25 | US9796723, 25 | US10011604, 25 | U...)
Affinity DataIC50: 13.8nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails
US Patent