BDBM200504 US9670231, 1.32

SMILES CN(C)[C@@H]1CN(Cc2ccc(cc2C(F)(F)F)C(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)CCN1

InChI Key InChIKey=SABATKMFVISBCV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 200504   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Beigene

US Patent
LigandPNGBDBM200504(US9670231, 1.32)
Affinity DataIC50: 13nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM200504(US9670231, 1.32)
Affinity DataIC50: 2.5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Beigene

US Patent
LigandPNGBDBM200504(US9670231, 1.32)
Affinity DataIC50: 1.5nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Beigene

US Patent
LigandPNGBDBM200504(US9670231, 1.32)
Affinity DataIC50: 0.470nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM200504(US9670231, 1.32)
Affinity DataIC50: 1.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent