BDBM19817 (1R,2R)-N-(cyanomethyl)-2-[(phenylsulfanyl)methyl]cyclohexane-1-carboxamide::Cyclohexanecarboxamide derivative, 12a::racemic mixture

SMILES O=C(NCC#N)[C@@H]1CCCC[C@H]1CSc1ccccc1

InChI Key InChIKey=BFAFBMJYAAHSML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19817   

TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19817(racemic mixture | (1R,2R)-N-(cyanomethyl)-2-[(phen...)
Affinity DataIC50: 172nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19817(racemic mixture | (1R,2R)-N-(cyanomethyl)-2-[(phen...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19817(racemic mixture | (1R,2R)-N-(cyanomethyl)-2-[(phen...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed