BDBM198144 5-(3-(3-Nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(pyridin-3-yl)-4,5-dihydropyrazole-1-carbothioamide (6f)

SMILES NC(=S)N1N=C(CC1c1cn(nc1-c1cccc(c1)[N+]([O-])=O)-c1ccccc1)c1cccnc1

InChI Key InChIKey=GUVDXIKCMBKYPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198144   

TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198144(5-(3-(3-Nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(...)
Affinity DataIC50: 4.45E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed