BDBM198139 5-(1,3-Diphenyl-1H-pyrazol-4-yl)-3-(pyridin-3-yl)-4,5-dihydropyrazole-1-carbothioamide (6a)

SMILES NC(=S)N1N=C(CC1c1cn(nc1-c1ccccc1)-c1ccccc1)c1cccnc1

InChI Key InChIKey=FMNLRZBFQBKFIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198139   

TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198139(5-(1,3-Diphenyl-1H-pyrazol-4-yl)-3-(pyridin-3-yl)-...)
Affinity DataIC50: 2.45E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed