BDBM198138 Ethyl 4-(3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)-2-oxo-6-(pyridin-3-yl)cyclohex-3-enecarboxylate (5i)

SMILES CCOC(=O)C1C(CC(=CC1=O)c1cn(nc1-c1ccc(OC)cc1)-c1ccccc1)c1cccnc1

InChI Key InChIKey=UALNQCWOQINFQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198138   

TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198138(Ethyl 4-(3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4...)
Affinity DataIC50: 4.28E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
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PubMed