BDBM198099 BDBM198100::US9221795, 95

SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(Cl)ccc(Cl)c2c(=O)n1-c1cnc(N)cc1C

InChI Key InChIKey=HOHNTFDVJDSBDW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 198099   

LigandPNGBDBM198099(US9221795, 95 | BDBM198100)
Affinity DataIC50: 4nMpH: 7.4Assay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

LigandPNGBDBM198099(US9221795, 95 | BDBM198100)
Affinity DataIC50: 1nMpH: 7.4Assay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

LigandPNGBDBM198099(US9221795, 95 | BDBM198100)
Affinity DataIC50: 28nMpH: 7.4Assay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

LigandPNGBDBM198099(US9221795, 95 | BDBM198100)
Affinity DataIC50: 3nMpH: 7.4Assay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent