BDBM198073 BDBM198074::US9221795, 69

SMILES Cc1c(F)cncc1-n1c(nc2cccc(Cl)c2c1=O)[C@@H](Nc1nc(N)nc(N)c1C#N)C1CC1

InChI Key InChIKey=WGAFHSBUSIMICN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198073   

LigandPNGBDBM198073(US9221795, 69 | BDBM198074)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

LigandPNGBDBM198073(US9221795, 69 | BDBM198074)
Affinity DataIC50: 3nMpH: 7.4Assay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent