BDBM19807 CHEMBL100563::benzyl N-[(1S)-1-({1-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanoyl]-4-oxopyrrolidin-3-yl}carbamoyl)-3-methylbutyl]carbamate::pyrrolidinone analogue, 24
SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CN(CC1=O)C(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
InChI Key InChIKey=GXENQLUSOCKXDN-UHFFFAOYSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 19807
Affinity DataKi: 2nMAssay Description:Inhibitory activity against Cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -11.7kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Affinity for human Cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Affinity for human Cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nM ΔG°: >-8.10kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Affinity for human Cathepsin BMore data for this Ligand-Target Pair