BDBM19800 benzyl N-[(1S)-3-methyl-1-[(2-oxocyclopentyl)carbamoyl]butyl]carbamate::carbocyclic analogue, 7

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCCC1=O

InChI Key InChIKey=FETGIINWKFBKIT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19800   

TargetCathepsin K(Human)
Gsk

LigandPNGBDBM19800(benzyl N-[(1S)-3-methyl-1-[(2-oxocyclopentyl)carba...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.75kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin B(Human)
Gsk

LigandPNGBDBM19800(benzyl N-[(1S)-3-methyl-1-[(2-oxocyclopentyl)carba...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.75kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gsk

LigandPNGBDBM19800(benzyl N-[(1S)-3-methyl-1-[(2-oxocyclopentyl)carba...)
Affinity DataKi: >1.00E+4nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gsk

LigandPNGBDBM19800(benzyl N-[(1S)-3-methyl-1-[(2-oxocyclopentyl)carba...)
Affinity DataKi: >1.00E+4nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed