BDBM196661 US10202399, Example 21::US10463663, Example 17::US11129828, Example 17::US9212147, 21::US9290456, 17::US9931340, Example 17
SMILES Oc1cc(CCc2ccc(F)cc2F)n[nH]c1=O
InChI Key InChIKey=OJTADJYTNWQVQR-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 196661
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair