BDBM196020 US9206199, 125

SMILES Fc1ccc([C@@H]2CN3CCN(C[C@@H]3CO2)C(=O)Cc2cnc(nc2)-n2cnnn2)c(Cl)c1[N+]#[C-]

InChI Key InChIKey=PDTRGIAVWPRAGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196020   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM196020(US9206199, 125)
Affinity DataIC50: 60nMAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
Go to US Patent