BDBM195679 US9206173, 2441

SMILES COn1c(NC(C(C)C)c2ccc(Cl)cc2)nc2CCN(Cc2c1=O)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=DCCOCVJECZDOOW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195679   

TargetProlactin-releasing peptide receptor(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195679(US9206173, 2441)
Affinity DataIC50: 4.49E+3nMpH: 7.4 T: 2°CAssay Description:HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details
Go to US Patent

TargetProlactin-releasing peptide receptor(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195679(US9206173, 2441)
Affinity DataKi:  37nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details
Go to US Patent