BDBM195630 US9206173, 2392

SMILES COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)\C=N\c1ccc(Cl)cc1

InChI Key InChIKey=OSYXZFXPUGWOFF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195630   

TargetProlactin-releasing peptide receptor(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195630(US9206173, 2392)
Affinity DataIC50: 5.79E+3nMpH: 7.4 T: 2°CAssay Description:HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details
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TargetProlactin-releasing peptide receptor(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195630(US9206173, 2392)
Affinity DataKi:  12nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2016
Entry Details
Go to US Patent