BDBM194206 US9200001, 122
SMILES Cc1nc(C)n(n1)-c1cc(nc(OCCF)n1)[C@H]1C[C@@H]1c1nc2ccccc2n1C
InChI Key InChIKey=CXJDZIQSRMFJCQ-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 194206
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 1.20nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exper...More data for this Ligand-Target Pair