BDBM194127 US9200001, 43
SMILES COc1ccc(nc1)C1CC1c1cc(nc(C)n1)-n1nc(C)nc1Cc1ccc(OC)c(OC)c1
InChI Key InChIKey=CDZBKSOWBOQMTN-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 194127
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.390nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exper...More data for this Ligand-Target Pair