BDBM193772 US9670208, Example 398 4-(3-(2-fluorobenzyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-2-amine

SMILES Fc1ccccc1Cc1nnc2cc(ccn12)-c1ccnc(NC2CCOCC2)n1

InChI Key InChIKey=VBYMTVCXMFSICP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193772   

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM193772(US9670208, Example 398 4-(3-(2-fluorobenzyl)-[1,2,...)
Affinity DataIC50: 3nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails
US Patent