BDBM193743 Ethyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1H-pyrazol-1-yl)phenyl)hydrazono)hexanoate (11)

SMILES CCCC(=O)C(=N\Nc1cccc(c1)-n1nc(C(=O)Nc2nnc(s2)S(N)(=O)=O)c(C(=O)Nc2nnc(s2)S(N)(=O)=O)c1-c1ccccc1)\C(=O)OCC

InChI Key InChIKey=JKYUBDOQKGVDSH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 193743   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM193743(Ethyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl...)
Affinity DataKi:  84nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM193743(Ethyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl...)
Affinity DataKi:  246nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM193743(Ethyl 3-oxo-2-(2-(3-(5-phenyl-3,4-bis((5-sulfamoyl...)
Affinity DataKi:  884nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed