BDBM192718 HG-9-91-01 derivative, 7

SMILES COc1ccc(nc1)N1C(=O)N(Cc2cnc(Nc3ccc(cc3OC(C)C)C3CCN(C)CC3)nc12)c1c(C)cccc1C

InChI Key InChIKey=DVHMVHIBLHFENK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192718   

TargetSerine/threonine-protein kinase SIK2(Human)
Broad Institute

LigandPNGBDBM192718(HG-9-91-01 derivative, 7)
Affinity DataIC50: 7.00E+3nMpH: 8.0Assay Description:IC50‘s for HG-9-91-01 derivatives were measured by Caliper-based mobility shift assay (PerkinElmer). For these experiments, full length His6-MBP...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-10(Human)
Broad Institute

LigandPNGBDBM192718(HG-9-91-01 derivative, 7)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed