BDBM19271 Acridone-Based Inhibitor, 8c::N-benzyl-9-oxo-9,10-dihydroacridine-3-carboxamide

SMILES O=C(NCc1ccccc1)c1ccc2c(c1)[nH]c1ccccc1c2=O

InChI Key InChIKey=YUICSGTVFUPFFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19271   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb

LigandPNGBDBM19271(N-benzyl-9-oxo-9,10-dihydroacridine-3-carboxamide ...)
Affinity DataIC50: 2.20E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2007
Entry Details Article
PubMed