BDBM192536 US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}cyclopentanecarboxamide

SMILES Clc1ccc(cc1)-n1c(nc2c(ncnc12)N1CCC(CC1)NC(=O)C1CCCC1)-c1ccccc1Cl

InChI Key InChIKey=XCAAVBMCEMDRAB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192536   

TargetCannabinoid receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM192536(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM192536(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  1.54nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM192536(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor (unknown origin) expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM192536(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  60.2nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
Go to US Patent