BDBM191855 US9187428, 83

SMILES CNC(=O)c1cc(CSc2nc(NC[C@H](O)CO)c(C#N)c(-c3ccccc3)c2C#N)ccn1

InChI Key InChIKey=UGHXOTLFXUPIFS-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191855   

TargetAdenosine receptor A1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM191855(US9187428, 83)
Affinity DataEC50:  0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosine receptor A2a(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM191855(US9187428, 83)
Affinity DataEC50:  2.18E+3nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosine receptor A2b(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM191855(US9187428, 83)
Affinity DataEC50:  593nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
In DepthDetails
US Patent