BDBM191631 US9182402, 5

SMILES [O-][N+](=O)c1ccc(cc1)C1Nc2c(cccc2C(F)(F)F)C2C=CCC12

InChI Key InChIKey=VJDUKWHSBOBGIY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191631   

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191631(US9182402, 5)
Affinity DataIC50: 570nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191631(US9182402, 5)
Affinity DataIC50: 3.12E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191631(US9182402, 5)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent