BDBM191249 US9181272, 157::US9181272, 158::US9181272, 19

SMILES CC(O)c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O

InChI Key InChIKey=BXCSIMNHTKLBRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191249   

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191249(US9181272, 157 | US9181272, 158 | US9181272, 19)
Affinity DataIC50: 10nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191249(US9181272, 157 | US9181272, 158 | US9181272, 19)
Affinity DataIC50: 6.60nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191249(US9181272, 157 | US9181272, 158 | US9181272, 19)
Affinity DataIC50: 6.90nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In DepthDetails
US Patent