BDBM191192 US9181266, 61

SMILES Fc1ccc2C(=O)C3(Cc2c1)CCN(CC(=O)NCc1nc2CCOCc2c(=O)[nH]1)CC3

InChI Key InChIKey=MPGRGIIZXCNTKV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 191192   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Novartis

US Patent
LigandPNGBDBM191192(US9181266, 61)
Affinity DataIC50: 25nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Novartis

US Patent
LigandPNGBDBM191192(US9181266, 61)
Affinity DataIC50: 8nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Novartis

US Patent
LigandPNGBDBM191192(US9181266, 61)
Affinity DataIC50: 6.50E+3nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Novartis

US Patent
LigandPNGBDBM191192(US9181266, 61)
Affinity DataIC50: 1.90E+4nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
US Patent