BDBM191088 US9181258, 43

SMILES NCCC1CNC(=O)c2cc(c(-c3ccc(O)cc3)n12)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=PMKXIEFCLZIQLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191088   

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM191088(US9181258, 43)
Affinity DataIC50: 12nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM191088(US9181258, 43)
Affinity DataIC50: 21nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent