BDBM191076 US9181258, 85

SMILES NCC[C@H]1CNC(=O)c2cc(c(-c3ccsc3)n12)-c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=UPTADSCUUNQNDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191076   

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM191076(US9181258, 85)
Affinity DataIC50: 12nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM191076(US9181258, 85)
Affinity DataIC50: 69nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent