BDBM19037 6-(1-{2-[(dimethylamino)methyl]phenyl}piperidin-4-yl)-1-(4-methoxyphenyl)-7-oxo-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3-carboxamide::Pyrazole-based inhibitor containing N-arylpiperidiny, 16b

SMILES COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C3CCN(CC3)c3ccccc3CN(C)C)C(=O)c12

InChI Key InChIKey=QLIJAYGAJCPYAJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19037   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM19037(6-(1-{2-[(dimethylamino)methyl]phenyl}piperidin-4-...)
Affinity DataKi:  0.410nM ΔG°:  -12.7kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed