BDBM190322 US9670201, 78 3-cyano-N-(3-((1R,5S,8r)-3-isobutyryl-3-azabicyclo[3.2.1]octan-8-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-4-methoxybenzamide

SMILES COc1ccc(cc1C#N)C(=O)Nc1cnc2n(C)cc(C3C4CC[C@H]3CN(C4)C(=O)C(C)C)c2c1C(F)(F)F

InChI Key InChIKey=CKMZKOSHGLFDHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190322   

TargetNuclear receptor ROR-gamma(Human)
Pfizer

US Patent
LigandPNGBDBM190322(US9670201, 78 3-cyano-N-(3-((1R,5S,8r)-3-isobutyry...)
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:Specifically, in one embodiment the aforementioned assay was performed as outlined below. The assay was carried out in black polystyrene, 384-well pl...More data for this Ligand-Target Pair
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US Patent